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Basal expression of interferon regulatory factor 1 drives intrinsic hepatocyte resistance to multiple RNA viruses

Current paradigms of cell intrinsic immunity to RNA viruses center on virus-triggered inducible antiviral responses initiated by RIG-I-like receptors (RLRs) or Toll-like receptors (TLRs) that sense pathogen-associated molecular patterns, and signal downstream through interferon regulatory factors (I...

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Detalles Bibliográficos
Autores principales:	Yamane, Daisuke, Feng, Hui, Rivera-Serrano, Efraín E., Selitsky, Sara R., Hirai-Yuki, Asuka, Das, Anshuman, McKnight, Kevin L., Misumi, Ichiro, Hensley, Lucinda, Lovell, William, González-López, Olga, Suzuki, Ryosuke, Matsuda, Mami, Nakanishi, Hiroki, Ohto-Nakanishi, Takayo, Hishiki, Takayuki, Wauthier, Eliane, Oikawa, Tsunekazu, Morita, Kouichi, Reid, Lola M., Sethupathy, Praveen, Kohara, Michinori, Whitmire, Jason K., Lemon, Stanley M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588457/ https://www.ncbi.nlm.nih.gov/pubmed/30988429 http://dx.doi.org/10.1038/s41564-019-0425-6

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