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Studies of the oligomerisation mechanism of a cystatin-based engineered protein scaffold

Engineered protein scaffolds are an alternative to monoclonal antibodies in research and drug design due to their small size, ease of production, versatility, and specificity for chosen targets. One key consideration when engineering such proteins is retaining the original scaffold structure and sta...

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Detalles Bibliográficos
Autores principales: Zalar, Matja, Indrakumar, Sowmya, Levy, Colin W., Tunnicliffe, Richard B., Peters, Günther H. J., Golovanov, Alexander P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588553/
https://www.ncbi.nlm.nih.gov/pubmed/31227800
http://dx.doi.org/10.1038/s41598-019-45565-6