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Studies of the oligomerisation mechanism of a cystatin-based engineered protein scaffold
Engineered protein scaffolds are an alternative to monoclonal antibodies in research and drug design due to their small size, ease of production, versatility, and specificity for chosen targets. One key consideration when engineering such proteins is retaining the original scaffold structure and sta...
Autores principales: | Zalar, Matja, Indrakumar, Sowmya, Levy, Colin W., Tunnicliffe, Richard B., Peters, Günther H. J., Golovanov, Alexander P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588553/ https://www.ncbi.nlm.nih.gov/pubmed/31227800 http://dx.doi.org/10.1038/s41598-019-45565-6 |
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