A fast and specific fluorescent probe for thioredoxin reductase that works via disulphide bond cleavage

Small molecule probes are indispensable tools to explore diverse cellular events. However, finding a specific probe of a target remains a high challenge. Here we report the discovery of Fast-TRFS, a specific and superfast fluorogenic probe of mammalian thioredoxin reductase, a ubiquitous enzyme invo...

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Detalles Bibliográficos
Autores principales: Li, Xinming, Zhang, Baoxin, Yan, Chaoxian, Li, Jin, Wang, Song, Wei, Xiangxu, Jiang, Xiaoyan, Zhou, Panpan, Fang, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588570/
https://www.ncbi.nlm.nih.gov/pubmed/31227705
http://dx.doi.org/10.1038/s41467-019-10807-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588570/
https://www.ncbi.nlm.nih.gov/pubmed/31227705
http://dx.doi.org/10.1038/s41467-019-10807-8

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