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Conversion of human and mouse fibroblasts into lung-like epithelial cells

Cell lineage conversion of fibroblasts to specialized cell types through transdifferentiation may provide a fast and alternative cell source for regenerative medicine. Here we show that transient transduction of fibroblasts with the four reprogramming factors (Oct4, Sox2, Klf4, and c-Myc) in additio...

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Detalles Bibliográficos
Autores principales: Wong, Amy P., Shojaie, Sharareh, Liang, Qin, Xia, Sunny, Di Paola, Michelle, Ahmadi, Saumel, Bilodeau, Claudia, Garner, Jodi, Post, Martin, Duchesneau, Pascal, Waddell, Thomas K., Bear, Christine E., Nagy, Andras, Rossant, Janet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588580/
https://www.ncbi.nlm.nih.gov/pubmed/31227724
http://dx.doi.org/10.1038/s41598-019-45195-y