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Conversion of human and mouse fibroblasts into lung-like epithelial cells
Cell lineage conversion of fibroblasts to specialized cell types through transdifferentiation may provide a fast and alternative cell source for regenerative medicine. Here we show that transient transduction of fibroblasts with the four reprogramming factors (Oct4, Sox2, Klf4, and c-Myc) in additio...
Autores principales: | Wong, Amy P., Shojaie, Sharareh, Liang, Qin, Xia, Sunny, Di Paola, Michelle, Ahmadi, Saumel, Bilodeau, Claudia, Garner, Jodi, Post, Martin, Duchesneau, Pascal, Waddell, Thomas K., Bear, Christine E., Nagy, Andras, Rossant, Janet |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588580/ https://www.ncbi.nlm.nih.gov/pubmed/31227724 http://dx.doi.org/10.1038/s41598-019-45195-y |
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