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BioTarget: A Computational Framework Identifying Cancer Type Specific Transcriptional Targets of Immune Response Pathways

Transcriptome data can provide information on signaling pathways active in cancers, but new computational tools are needed to more accurately quantify pathway activity and identify tissue-specific pathway features. We developed a computational method called “BioTarget” that incorporates ChIP-seq dat...

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Detalles Bibliográficos
Autores principales: Hoang, Tham H., Zhao, Yue, Lam, Yiu, Piekos, Stephanie, Han, Yueh-Chiang, Reilly, Cameron, Joshi, Pujan, Hong, Seung-Hyun, Sung, Chang Ohk, Giardina, Charles, Shin, Dong-Guk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588588/
https://www.ncbi.nlm.nih.gov/pubmed/31227749
http://dx.doi.org/10.1038/s41598-019-45304-x