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Phrixotrix luciferase and 6′-aminoluciferins reveal a larger luciferin phenolate binding site and provide novel far-red combinations for bioimaging purposes

How the unique luciferase of Phrixothrix hirtus (PxRE) railroad worm catalyzes the emission of red bioluminescence using the same luciferin of fireflies, remains a mystery. Although PxRE luciferase is a very attractive tool for bioanalysis and bioimaging in hemoglobin rich tissues, it displays lower...

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Detalles Bibliográficos
Autores principales: Bevilaqua, V. R., Matsuhashi, T., Oliveira, G., Oliveira, P. S. L., Hirano, T., Viviani, V. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588592/
https://www.ncbi.nlm.nih.gov/pubmed/31227722
http://dx.doi.org/10.1038/s41598-019-44534-3