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Phrixotrix luciferase and 6′-aminoluciferins reveal a larger luciferin phenolate binding site and provide novel far-red combinations for bioimaging purposes
How the unique luciferase of Phrixothrix hirtus (PxRE) railroad worm catalyzes the emission of red bioluminescence using the same luciferin of fireflies, remains a mystery. Although PxRE luciferase is a very attractive tool for bioanalysis and bioimaging in hemoglobin rich tissues, it displays lower...
Autores principales: | Bevilaqua, V. R., Matsuhashi, T., Oliveira, G., Oliveira, P. S. L., Hirano, T., Viviani, V. R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588592/ https://www.ncbi.nlm.nih.gov/pubmed/31227722 http://dx.doi.org/10.1038/s41598-019-44534-3 |
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