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Integrative inference of subclonal tumour evolution from single-cell and bulk sequencing data
Understanding the clonal architecture and evolutionary history of a tumour poses one of the key challenges to overcome treatment failure due to resistant cell populations. Previously, studies on subclonal tumour evolution have been primarily based on bulk sequencing and in some recent cases on singl...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588593/ https://www.ncbi.nlm.nih.gov/pubmed/31227714 http://dx.doi.org/10.1038/s41467-019-10737-5 |