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Endothelial cells promote 3D invasion of GBM by IL-8-dependent induction of cancer stem cell properties

Rapid growth and perivascular invasion are hallmarks of glioblastoma (GBM) that have been attributed to the presence of cancer stem-like cells (CSCs) and their association with the perivascular niche. However, the mechanisms by which the perivascular niche regulates GBM invasion and CSCs remain poor...

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Detalles Bibliográficos
Autores principales: McCoy, Michael G., Nyanyo, Dennis, Hung, Carol K., Goerger, Julian Palacios, R. Zipfel, Warren, Williams, Rebecca M., Nishimura, Nozomi, Fischbach, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588602/
https://www.ncbi.nlm.nih.gov/pubmed/31227783
http://dx.doi.org/10.1038/s41598-019-45535-y