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α7 nicotinic acetylcholine receptor upregulation by anti-apoptotic Bcl-2 proteins

Nicotinic acetylcholine receptors (nAChRs) mediate and modulate synaptic transmission throughout the brain, and contribute to learning, memory, and behavior. Dysregulation of α7-type nAChRs in neuropsychiatric as well as immunological and oncological diseases makes them attractive targets for pharma...

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Detalles Bibliográficos
Autores principales: Dawe, G. Brent, Yu, Hong, Gu, Shenyan, Blackler, Alissa N., Matta, Jose A., Siuda, Edward R., Rex, Elizabeth B., Bredt, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588605/
https://www.ncbi.nlm.nih.gov/pubmed/31227712
http://dx.doi.org/10.1038/s41467-019-10723-x