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α7 nicotinic acetylcholine receptor upregulation by anti-apoptotic Bcl-2 proteins
Nicotinic acetylcholine receptors (nAChRs) mediate and modulate synaptic transmission throughout the brain, and contribute to learning, memory, and behavior. Dysregulation of α7-type nAChRs in neuropsychiatric as well as immunological and oncological diseases makes them attractive targets for pharma...
Autores principales: | Dawe, G. Brent, Yu, Hong, Gu, Shenyan, Blackler, Alissa N., Matta, Jose A., Siuda, Edward R., Rex, Elizabeth B., Bredt, David S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588605/ https://www.ncbi.nlm.nih.gov/pubmed/31227712 http://dx.doi.org/10.1038/s41467-019-10723-x |
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