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Astrocyte alterations in neurodegenerative pathologies and their modeling in human induced pluripotent stem cell platforms

Astrocytes are the most abundant cell type in the brain. They were long considered only as passive support for neuronal cells. However, recent data have revealed many active roles for these cells both in maintenance of the normal physiological homeostasis in the brain as well as in neurodegeneration...

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Detalles Bibliográficos
Autores principales: Oksanen, Minna, Lehtonen, Sarka, Jaronen, Merja, Goldsteins, Gundars, Hämäläinen, Riikka H., Koistinaho, Jari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588647/
https://www.ncbi.nlm.nih.gov/pubmed/31016348
http://dx.doi.org/10.1007/s00018-019-03111-7