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Astrocyte alterations in neurodegenerative pathologies and their modeling in human induced pluripotent stem cell platforms
Astrocytes are the most abundant cell type in the brain. They were long considered only as passive support for neuronal cells. However, recent data have revealed many active roles for these cells both in maintenance of the normal physiological homeostasis in the brain as well as in neurodegeneration...
Autores principales: | Oksanen, Minna, Lehtonen, Sarka, Jaronen, Merja, Goldsteins, Gundars, Hämäläinen, Riikka H., Koistinaho, Jari |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588647/ https://www.ncbi.nlm.nih.gov/pubmed/31016348 http://dx.doi.org/10.1007/s00018-019-03111-7 |
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