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Pharmacologic targeting of β-catenin improves fracture healing in old mice

β-catenin protein needs to be precisely regulated for effective fracture repair. The pace of fracture healing slows with age, associated with a transient increase in β-catenin during the initial phase of the repair process. Here we examined the ability of pharmacologic agents that target β-catenin t...

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Detalles Bibliográficos
Autores principales: Kwak, Yoon Hae, Barrientos, Tomasa, Furman, Bridgette, Zhang, Hazel, Puviindran, Vijitha, Cutcliffe, Hattie, Herfarth, Jonas, Nwankwo, Eugene, Alman, Benjamin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588693/
https://www.ncbi.nlm.nih.gov/pubmed/31227757
http://dx.doi.org/10.1038/s41598-019-45339-0