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Pharmacologic targeting of β-catenin improves fracture healing in old mice
β-catenin protein needs to be precisely regulated for effective fracture repair. The pace of fracture healing slows with age, associated with a transient increase in β-catenin during the initial phase of the repair process. Here we examined the ability of pharmacologic agents that target β-catenin t...
Autores principales: | Kwak, Yoon Hae, Barrientos, Tomasa, Furman, Bridgette, Zhang, Hazel, Puviindran, Vijitha, Cutcliffe, Hattie, Herfarth, Jonas, Nwankwo, Eugene, Alman, Benjamin A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588693/ https://www.ncbi.nlm.nih.gov/pubmed/31227757 http://dx.doi.org/10.1038/s41598-019-45339-0 |
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