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Apoptosis of cancer cells is triggered by selective crosslinking and inhibition of receptor tyrosine kinases
Receptor tyrosine kinases (RTK) have been the most prevalent therapeutic targets in anti-cancer drug development. However, the emergence of drug resistance toward single target RTK inhibitors remains a major challenge to achieve long-term remissions. Development of alternative RTK inhibitory strateg...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588694/ https://www.ncbi.nlm.nih.gov/pubmed/31263775 http://dx.doi.org/10.1038/s42003-019-0484-5 |