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Lugdunin amplifies innate immune responses in the skin in synergy with host- and microbiota-derived factors

Recently our groups discovered lugdunin, a new cyclic peptide antibiotic that inhibits Staphylococcus aureus epithelial colonization in humans and rodents. In this work, we analyzed its immuno-modulatory and antimicrobial potential as a single agent or in combination with other microbiota- or host-d...

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Detalles Bibliográficos
Autores principales: Bitschar, Katharina, Sauer, Birgit, Focken, Jule, Dehmer, Hanna, Moos, Sonja, Konnerth, Martin, Schilling, Nadine A., Grond, Stephanie, Kalbacher, Hubert, Kurschus, Florian C., Götz, Friedrich, Krismer, Bernhard, Peschel, Andreas, Schittek, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588697/
https://www.ncbi.nlm.nih.gov/pubmed/31227691
http://dx.doi.org/10.1038/s41467-019-10646-7