Construction of an immunotoxin via site-specific conjugation of anti-Her2 IgG and engineered Pseudomonas exotoxin A

BACKGROUND: Immunotoxins consisting of a toxin from bacteria or plants and a targeting module have been developed as potent anti-cancer therapeutics. The majority of them, especially those in preclinical or clinical testing stages, are fusion proteins of a toxin and antibody fragment. Immunotoxins b...

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Detalles Bibliográficos
Autores principales: Lee, Byeong Sung, Lee, Yumi, Park, Jisoo, Jeong, Bo Seok, Jo, Migyeong, Jung, Sang Taek, Yoo, Tae Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588878/
https://www.ncbi.nlm.nih.gov/pubmed/31285754
http://dx.doi.org/10.1186/s13036-019-0188-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588878/
https://www.ncbi.nlm.nih.gov/pubmed/31285754
http://dx.doi.org/10.1186/s13036-019-0188-x

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