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Amino acidic substitutions in the polymerase N-terminal region of a reassortant betanodavirus strain causing poor adaptation to temperature increase

Nervous necrosis virus (NNV), Genus Betanodavirus, is the causative agent of viral encephalopathy and retinopathy (VER), a neuropathological disease that causes fish mortalities worldwide. The NNV genome is composed of two single-stranded RNA molecules, RNA1 and RNA2, encoding the RNA polymerase and...

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Detalles Bibliográficos
Autores principales: Souto, Sandra, Vázquez-Salgado, Lucía, Olveira, José G., Bandín, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588924/
https://www.ncbi.nlm.nih.gov/pubmed/31227007
http://dx.doi.org/10.1186/s13567-019-0669-4