Methods to adjust for multiple comparisons in the analysis and sample size calculation of randomised controlled trials with multiple primary outcomes

BACKGROUND: Multiple primary outcomes may be specified in randomised controlled trials (RCTs). When analysing multiple outcomes it’s important to control the family wise error rate (FWER). A popular approach to do this is to adjust the p-values corresponding to each statistical test used to investig...

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Detalles Bibliográficos
Autores principales: Vickerstaff, Victoria, Omar, Rumana Z., Ambler, Gareth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588937/
https://www.ncbi.nlm.nih.gov/pubmed/31226934
http://dx.doi.org/10.1186/s12874-019-0754-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588937/
https://www.ncbi.nlm.nih.gov/pubmed/31226934
http://dx.doi.org/10.1186/s12874-019-0754-4

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