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A germline mutation in Rab43 gene identified from a cancer family predisposes to a hereditary liver-colon cancer syndrome

BACKGROUND: Hereditary cancer syndromes have inherited germline mutations which predispose to benign and malignant tumors. Understanding of the molecular causes in hereditary cancer syndromes has advanced cancer treatment and prevention. However, the causal genes of many hereditary cancer syndromes...

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Detalles Bibliográficos
Autores principales: Jiang, Yanting, Sun, Yue, Hu, Jiandong, Yu, Nan, Liu, Hui, Fan, Jiankun, Ning, Xuelian, Li, Yilan, Liu, Baogang, Sun, Yihua, Zhang, Jinwei, Qiu, Xiaohong, Fu, Songbin, Zhou, Chunshui, Xu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588942/
https://www.ncbi.nlm.nih.gov/pubmed/31226964
http://dx.doi.org/10.1186/s12885-019-5845-4