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Longitudinal immunosequencing in healthy people reveals persistent T cell receptors rich in highly public receptors
BACKGROUND: The adaptive immune system maintains a diversity of T cells capable of recognizing a broad array of antigens. Each T cell’s specificity for antigens is determined by its T cell receptors (TCRs), which together across all T cells form a repertoire of millions of unique receptors in each i...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588944/ https://www.ncbi.nlm.nih.gov/pubmed/31226930 http://dx.doi.org/10.1186/s12865-019-0300-5 |