Cargando…
Longitudinal immunosequencing in healthy people reveals persistent T cell receptors rich in highly public receptors
BACKGROUND: The adaptive immune system maintains a diversity of T cells capable of recognizing a broad array of antigens. Each T cell’s specificity for antigens is determined by its T cell receptors (TCRs), which together across all T cells form a repertoire of millions of unique receptors in each i...
Autores principales: | Chu, Nathaniel D., Bi, Haixin Sarah, Emerson, Ryan O., Sherwood, Anna M., Birnbaum, Michael E., Robins, Harlan S., Alm, Eric J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588944/ https://www.ncbi.nlm.nih.gov/pubmed/31226930 http://dx.doi.org/10.1186/s12865-019-0300-5 |
Ejemplares similares
-
LB17. Immunosequencing of the T-Cell Receptor Repertoire Reveals Signatures Specific for Diagnosis and Characterization of Early Lyme Disease
por: Dalai, Sudeb C, et al.
Publicado: (2021) -
Immune monitoring technology primer: immunosequencing
por: Kirsch, Ilan
Publicado: (2015) -
A Public Database of Memory and Naive B-Cell Receptor Sequences
por: DeWitt, William S., et al.
Publicado: (2016) -
Anti-Sars-Cov-2 Antibody and T-Cell Responses Using Deep T-Cell Receptor Immunosequencing after Vaccination Among Healthy Individuals and Patients with Multiple Myeloma or Lymphoma
por: Takamatsu, Hiroyuki, et al.
Publicado: (2022) -
Annotation of pseudogenic gene segments by massively parallel sequencing of rearranged lymphocyte receptor loci
por: Dean, Jared, et al.
Publicado: (2015)