Power estimations for non-primary outcomes in randomised clinical trials

Objective and methods: It is rare that trialists report power estimations of non-primary outcomes. In the present article, we will describe how to define a valid hierarchy of outcomes in a randomised clinical trial, to limit problems with Type I and Type II errors, using considerations on the clinic...

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Detalles Bibliográficos
Autores principales: Jakobsen, Janus Christian, Ovesen, Christian, Winkel, Per, Hilden, Jørgen, Gluud, Christian, Wetterslev, Jørn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Research Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588976/
https://www.ncbi.nlm.nih.gov/pubmed/31175197
http://dx.doi.org/10.1136/bmjopen-2018-027092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588976/
https://www.ncbi.nlm.nih.gov/pubmed/31175197
http://dx.doi.org/10.1136/bmjopen-2018-027092

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