Mechanism of Microbicidal Action of E-101 Solution, a Myeloperoxidase-Mediated Antimicrobial, and Its Oxidative Products

E-101 solution is a first-in-class myeloperoxidase-mediated antimicrobial developed for topical application. It is composed of porcine myeloperoxidase (pMPO), glucose oxidase (GO), glucose, sodium chloride, and specific amino acids in an aqueous solution. Once activated, the reactive species hydroge...

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Detalles Bibliográficos
Autores principales: Denys, Gerald A., Devoe, Neil C., Gudis, Polyxeni, May, Meghan, Allen, Robert C., Stephens, Jackson T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Bacterial Infections
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589053/
https://www.ncbi.nlm.nih.gov/pubmed/31010816
http://dx.doi.org/10.1128/IAI.00261-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589053/
https://www.ncbi.nlm.nih.gov/pubmed/31010816
http://dx.doi.org/10.1128/IAI.00261-19

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