β1 integrin is a sensor of blood flow direction

Endothelial cell (EC) sensing of fluid shear stress direction is a critical determinant of vascular health and disease. Unidirectional flow induces EC alignment and vascular homeostasis, whereas bidirectional flow has pathophysiological effects. ECs express several mechanoreceptors that respond to f...

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Detalles Bibliográficos
Autores principales: Xanthis, Ioannis, Souilhol, Celine, Serbanovic-Canic, Jovana, Roddie, Hannah, Kalli, Antreas C., Fragiadaki, Maria, Wong, Raymond, Shah, Dhruv R., Askari, Janet A., Canham, Lindsay, Akhtar, Nasreen, Feng, Shuang, Ridger, Victoria, Waltho, Jonathan, Pinteaux, Emmanuel, Humphries, Martin J., Bryan, Matthew T., Evans, Paul C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589088/
https://www.ncbi.nlm.nih.gov/pubmed/31076511
http://dx.doi.org/10.1242/jcs.229542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589088/
https://www.ncbi.nlm.nih.gov/pubmed/31076511
http://dx.doi.org/10.1242/jcs.229542

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