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MIR29B mediates epigenetic mechanisms of HBG gene activation

Sickle cell disease (SCD) affects over 2 million people worldwide with high morbidity and mortality in underdeveloped countries. Therapeutic interventions aimed at reactivating fetal haemoglobin (HbF) is an effective approach for improving survival and ameliorating the clinical severity of SCD. A cl...

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Detalles Bibliográficos
Autores principales: Starlard‐Davenport, Athena, Smith, Alana, Vu, Luan, Li, Biaoru, Pace, Betty S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589104/
https://www.ncbi.nlm.nih.gov/pubmed/30891745
http://dx.doi.org/10.1111/bjh.15870