Upregulation of miR-34a by Inhibition of IRE1α Has Protective Effect against Aβ-Induced Injury in SH-SY5Y Cells by Targeting Caspase-2

BACKGROUND: Neurotoxicity induced by the amyloid-β (Aβ) peptide is one of the most important pathological mechanisms of Alzheimer's disease (AD). Based on accumulating evidence in AD research, both endoplasmic reticulum stress (ER stress) and alterations in the microRNA (miRNA) network contribu...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Qianqian, Liu, Tingjiao, Yang, Shanshan, Zhang, Zhongling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589233/
https://www.ncbi.nlm.nih.gov/pubmed/31281568
http://dx.doi.org/10.1155/2019/2140427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589233/
https://www.ncbi.nlm.nih.gov/pubmed/31281568
http://dx.doi.org/10.1155/2019/2140427

Ejemplares similares