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Potential for Isolation of Immortalized Hepatocyte Cell Lines by Liver-Directed In Vivo Gene Delivery of Transposons in Mice

Isolation of hepatocytes and their culture in vitro represent important avenues to explore the function of such cells. However, these studies are often difficult to perform because of the inability of hepatocytes to proliferate in vitro. Immortalization of isolated hepatocytes is thus an important s...

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Detalles Bibliográficos
Autores principales: Sato, Masahiro, Saitoh, Issei, Inada, Emi, Nakamura, Shingo, Watanabe, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589260/
https://www.ncbi.nlm.nih.gov/pubmed/31281376
http://dx.doi.org/10.1155/2019/5129526