Cargando…

ELL2 Is Downregulated and Associated with Galactose-Deficient IgA1 in IgA Nephropathy

BACKGROUND: Galactose-deficient IgA1 (Gd-IgA1) is an important causal factor in IgA nephropathy; however, the underlying mechanism for the production of Gd-IgA1 is unknown. The elongation factor for RNA polymerase II (ELL2), which encoded a key component of the superelongation complex (SEC), drives...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Youxia, Zheng, Jie, Zhao, Na, Jia, Junya, Yan, Tiekun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589307/
https://www.ncbi.nlm.nih.gov/pubmed/31275443
http://dx.doi.org/10.1155/2019/2407067