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ELL2 Is Downregulated and Associated with Galactose-Deficient IgA1 in IgA Nephropathy
BACKGROUND: Galactose-deficient IgA1 (Gd-IgA1) is an important causal factor in IgA nephropathy; however, the underlying mechanism for the production of Gd-IgA1 is unknown. The elongation factor for RNA polymerase II (ELL2), which encoded a key component of the superelongation complex (SEC), drives...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589307/ https://www.ncbi.nlm.nih.gov/pubmed/31275443 http://dx.doi.org/10.1155/2019/2407067 |