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ZYZ-803 Mitigates Endoplasmic Reticulum Stress-Related Necroptosis after Acute Myocardial Infarction through Downregulating the RIP3-CaMKII Signaling Pathway

Acute myocardial infarction (AMI) is a leading cause of morbidity and mortality worldwide, and both cardiac necroptosis and endoplasmic reticulum stress (ERS) have been involved in the pathophysiology of AMI. ZYZ-803 is a hybrid molecule of a dual donor for gasotransmitters H(2)S and NO. The aim of...

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Detalles Bibliográficos
Autores principales: Chang, Lingling, Wang, Zhijun, Ma, Fenfen, Tran, Bahieu, Zhong, Rui, Xiong, Ying, Dai, Tao, Wu, Jian, Xin, Xiaoming, Guo, Wei, Xie, Ying, Mao, Yicheng, Zhu, Yi-Zhun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589311/
https://www.ncbi.nlm.nih.gov/pubmed/31281585
http://dx.doi.org/10.1155/2019/6173685