Cargando…
Sequencing abasic sites in DNA at single-nucleotide resolution
In DNA, the loss of a nucleobase by hydrolysis generates an abasic site. Formed as a result of DNA damage, as well as a key intermediate during the base excision repair pathway, abasic sites are frequent DNA lesions which can lead to mutations and strand breaks. Here we present snAP-seq, a chemical...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589398/ https://www.ncbi.nlm.nih.gov/pubmed/31209299 http://dx.doi.org/10.1038/s41557-019-0279-9 |