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Drug-likeness prediction of designed analogues of isoniazid standard targeting FabI enzyme regulation from P. falciparum
Fatty acid biosynthesis enzymes (Fab enzyme) are important targets for anti-malarial drug development. The present study describes the toxicity screening of designed novel analogues which inhibit FabI enzyme regulation, a protein with multifunctional property. New analogues were prepared using ChemD...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Biomedical Informatics
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589475/ https://www.ncbi.nlm.nih.gov/pubmed/31249440 http://dx.doi.org/10.6026/97320630015364 |