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Testing algorithm for identification of patients with TRK fusion cancer

The neurotrophic tyrosine receptor kinase (NTRK) gene family encodes three tropomyosin receptor kinases (TRKA, TRKB, TRKC) that contribute to central and peripheral nervous system development and function. NTRK gene fusions are oncogenic drivers of various adult and paediatric tumours. Several metho...

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Detalles Bibliográficos
Autores principales: Penault-Llorca, Frédérique, Rudzinski, Erin R, Sepulveda, Antonia R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589488/
https://www.ncbi.nlm.nih.gov/pubmed/31072837
http://dx.doi.org/10.1136/jclinpath-2018-205679