Implications of intrachromosomal amplification of chromosome 21 on outcome in pediatric acute lymphoblastic leukemia: Does it affect our patients too?

Intrachromosomal amplification (iAMP) of chromosome 21 entity is associated with a dismal outcome in B cell Acute Lymphoblastic Leukemia (B-ALL). This cytogenetic abnormality is caused by a novel mechanism; breakage-fusion-bridge cycles followed by chromothripsis along with major gross rearrangement...

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Detalles Bibliográficos
Autores principales: Al-Sweedan, Suleimman, Altahan, Rahaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589538/
https://www.ncbi.nlm.nih.gov/pubmed/31285807
http://dx.doi.org/10.4081/hr.2019.7826

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589538/
https://www.ncbi.nlm.nih.gov/pubmed/31285807
http://dx.doi.org/10.4081/hr.2019.7826

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