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ErbB4 tyrosine kinase inhibition impairs neuromuscular development in zebrafish embryos

Tyrosine kinase inhibitors are widely used in the clinic, but limited information is available about their toxicity in developing organisms. Here, we tested the effect of tyrosine kinase inhibitors targeting the ErbB receptors for their effects on developing zebrafish (Danio rerio) embryos. Embryos...

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Detalles Bibliográficos
Autores principales: Paatero, Ilkka, Veikkolainen, Ville, Mäenpää, Matias, Schmelzer, Etienne, Belting, Heinz-Georg, Pelliniemi, Lauri J., Elenius, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589560/
https://www.ncbi.nlm.nih.gov/pubmed/30462579
http://dx.doi.org/10.1091/mbc.E18-07-0460