Cargando…

ErbB4 tyrosine kinase inhibition impairs neuromuscular development in zebrafish embryos

Tyrosine kinase inhibitors are widely used in the clinic, but limited information is available about their toxicity in developing organisms. Here, we tested the effect of tyrosine kinase inhibitors targeting the ErbB receptors for their effects on developing zebrafish (Danio rerio) embryos. Embryos...

Descripción completa

Detalles Bibliográficos
Autores principales:	Paatero, Ilkka, Veikkolainen, Ville, Mäenpää, Matias, Schmelzer, Etienne, Belting, Heinz-Georg, Pelliniemi, Lauri J., Elenius, Klaus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589560/ https://www.ncbi.nlm.nih.gov/pubmed/30462579 http://dx.doi.org/10.1091/mbc.E18-07-0460

Ejemplares similares

Cell Death or Survival Promoted by Alternative Isoforms of ErbB4
por: Sundvall, Maria, et al.
Publicado: (2010)

Mutational Screening in Tyrosine-Kinase Domain of erbB1 And erbB2 Genes
por: ALONSO, Juan Manuel Fernández
Publicado: (2005)

The ErbB receptor tyrosine kinases and their roles in cancer
por: Hynes, NE
Publicado: (2003)

Negative regulation of ErbB family receptor tyrosine kinases
por: Sweeney, C, et al.
Publicado: (2004)

Proteolytic Processing of ErbB4 in Breast Cancer
por: Hollmén, Maija, et al.
Publicado: (2012)

Melatonin upregulates ErbB1 and ErbB4, two primary implantation receptors, in pre-implantation mouse embryos
por: Moshkdanian, Ghazaleh, et al.
Publicado: (2017)

Tyrosine kinase signalling in breast cancer: ErbB family receptor tyrosine kinases
por: Stern, David F
Publicado: (2000)

Neuregulin/ErbB regulate neuromuscular junction development by phosphorylation of α-dystrobrevin
por: Schmidt, Nadine, et al.
Publicado: (2011)

ErbB2 Is Necessary for Induction of Carcinoma Cell Invasion by Erbb Family Receptor Tyrosine Kinases
por: Spencer, Kathryn S.R., et al.
Publicado: (2000)

Modulation of ErbB2 Blockade in ErbB2-Positive Cancers: The Role of ErbB2 Mutations and PHLDA1
por: Li, Guangyuan, et al.
Publicado: (2014)

Conformational changes in receptor tyrosine kinase signaling: an ErbB garden of delights
por: Carraway, Kermit L, et al.
Publicado: (2009)

Co-Conserved Features Associated with cis Regulation of ErbB Tyrosine Kinases
por: Mirza, Amar, et al.
Publicado: (2010)

Chaperone-mediated destruction of erbB2: relevance to tyrosine kinase inhibitors
por: Gee, Julia MW
Publicado: (2002)

Irreversible tyrosine kinase inhibitors induce the endocytosis and downregulation of ErbB2
por: Ghosh, Chinmoy, et al.
Publicado: (2023)

Systemic Analysis of Gene Expression Profiles Identifies ErbB3 as a Potential Drug Target in Pediatric Alveolar Rhabdomyosarcoma
por: Nordberg, Janne, et al.
Publicado: (2012)

Cartilage regeneration in zebrafish depends on Nrg1/ErbB signaling pathway
por: Sapède, Dora, et al.
Publicado: (2023)

Removal of cell surface heparan sulfate increases TACE activity and cleavage of ErbB4 receptor
por: Määttä, Jorma A, et al.
Publicado: (2009)

Receptor tyrosine kinase profiling of ischemic heart identifies ROR1 as a potential therapeutic target
por: Heliste, Juho, et al.
Publicado: (2018)

Endocrine resistance in breast cancer: new roles for ErbB3 and ErbB4
por: Sutherland, Robert L
Publicado: (2011)

ErbB activation signatures as potential biomarkers for anti-ErbB3 treatment in HNSCC
por: Alvarado, Diego, et al.
Publicado: (2017)

Receptor Tyrosine Kinase ErbB2 Translocates into Mitochondria and Regulates Cellular Metabolism
por: Ding, Yan, et al.
Publicado: (2012)

Analysis of copy number loss of the ErbB4 receptor tyrosine kinase in glioblastoma
por: Jones, DeAnalisa C., et al.
Publicado: (2018)

Peptide G-Protein-Coupled Receptors and ErbB Receptor Tyrosine Kinases in Cancer
por: Moody, Terry W., et al.
Publicado: (2023)

Proliferation of Colorectal Cancer Is Promoted by Two Signaling Transduction Expression Patterns: ErbB2/ErbB3/AKT and MET/ErbB3/MAPK
por: Yao, Yong-Liang, et al.
Publicado: (2013)

Expression of oncogenes in thyroid tumours: coexpression of c-erbB2/neu and c-erbB.
por: Aasland, R., et al.
Publicado: (1988)

Nucleolin and ErbB2 inhibition reduces tumorigenicity of ErbB2-positive breast cancer
por: Wolfson, Eya, et al.
Publicado: (2018)

Nucleolin-binding by ErbB2 enhances tumorigenicity of ErbB2-positive breast cancer
por: Wolfson, Eya, et al.
Publicado: (2016)

A monoclonal antibody targeting ErbB2 domain III inhibits ErbB2 signaling and suppresses the growth of ErbB2-overexpressing breast tumors
por: Meng, Y, et al.
Publicado: (2016)

Constitutive Proteolysis of the ErbB-4 Receptor Tyrosine Kinase by a Unique, Sequential Mechanism
por: Vecchi, Manuela, et al.
Publicado: (1997)

A new solvate of afatinib, a specific inhibitor of the ErbB family of tyrosine kinases
por: Zeller, Matthias, et al.
Publicado: (2017)

The Role of ErbB Receptors in Infection
por: Ho, Jemima, et al.
Publicado: (2017)

Analyses in zebrafish embryos reveal that nanotoxicity profiles are dependent on surface-functionalization controlled penetrance of biological membranes
por: Paatero, Ilkka, et al.
Publicado: (2017)

FAK signaling is critical for ErbB-2/ErbB-3 receptor cooperation for oncogenic transformation and invasion
por: Benlimame, Naciba, et al.
Publicado: (2005)

ErbB1 and ErbB3 co-over expression as a prognostic factor in gastric cancer
por: Moghbeli, Meysam, et al.
Publicado: (2019)

NRG/ErbB signaling regulates neonatal muscle growth but not neuromuscular contractures in neonatal brachial plexus injury
por: Ho, Brendan L., et al.
Publicado: (2021)

erbB-2 antisense oligonucleotides inhibit the proliferation of breast carcinoma cells with erbB-2 oncogene amplification.
por: Colomer, R., et al.
Publicado: (1994)

Betacellulin-Induced Beta Cell Proliferation and Regeneration Is Mediated by Activation of ErbB-1 and ErbB-2 Receptors
por: Oh, Yoon Sin, et al.
Publicado: (2011)

Comparative oncology: ErbB-1 and ErbB-2 homologues in canine cancer are susceptible to cetuximab and trastuzumab targeting
por: Singer, Josef, et al.
Publicado: (2012)

Quantitative Analysis of ErbB1 and ErbB2 Genes Amplification by a High Performance Liquid Chromatography
por: Rasti, Mozhgan, et al.
Publicado: (2014)

Effects of ErbB2 Overexpression on the Proteome and ErbB Ligand-specific Phosphosignaling in Mammary Luminal Epithelial Cells
por: Worthington, Jenny, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_kfrte4d4co7ib8p8mgisqm9ai2