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A rapid computational approach identifies SPICE1 as an Aurora kinase substrate

Aurora kinases play a major role in mitosis by regulating diverse substrates. Defining their critical downstream targets is important in understanding Aurora kinase function. Here we have developed an unbiased computational approach to identify new Aurora kinase substrates based on phosphorylation s...

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Detalles Bibliográficos
Autores principales: Deretic, Jovana, Kerr, Alastair, Welburn, Julie P. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589576/
https://www.ncbi.nlm.nih.gov/pubmed/30485161
http://dx.doi.org/10.1091/mbc.E18-08-0495