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Uncoupling of transcriptomic and cytological differentiation in mouse spermatocytes with impaired meiosis

Cell differentiation is driven by changes in gene expression that manifest as changes in cellular phenotype or function. Altered cellular phenotypes, stemming from genetic mutations or other perturbations, are widely assumed to directly correspond to changes in the transcriptome and vice versa. Here...

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Detalles Bibliográficos
Autores principales: Fine, Alexander D., Ball, Robyn L., Fujiwara, Yasuhiro, Handel, Mary Ann, Carter, Gregory W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589690/
https://www.ncbi.nlm.nih.gov/pubmed/30649999
http://dx.doi.org/10.1091/mbc.E18-10-0681