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Dual RXR motifs regulate nerve growth factor–mediated intracellular retention of the delta opioid receptor

The delta opioid receptor (DOR), a physiologically relevant prototype for G protein–coupled receptors, is retained in intracellular compartments in neuronal cells. This retention is mediated by a nerve growth factor (NGF)-regulated checkpoint that delays the export of DOR from the trans-Golgi networ...

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Detalles Bibliográficos
Autores principales: Shiwarski, Daniel J., Crilly, Stephanie E., Dates, Andrew, Puthenveedu, Manojkumar A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589700/
https://www.ncbi.nlm.nih.gov/pubmed/30601694
http://dx.doi.org/10.1091/mbc.E18-05-0292