Modulation of VEGF-induced migration and network formation by lymphatic endothelial cells: Roles of platelets and podoplanin

Lymphatic endothelial cells (LEC) express the transmembrane receptor podoplanin whose only known endogenous ligand CLEC-2 is found on platelets. Both podoplanin and CLEC-2 are required for normal lymphangiogenesis as mice lacking either protein develop a blood-lymphatic mixing phenotype. We investig...

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Detalles Bibliográficos
Autores principales: Langan, Stacey A., Navarro-Núñez, Leyre, Watson, Steve P., Nash, Gerard B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589745/
https://www.ncbi.nlm.nih.gov/pubmed/28727496
http://dx.doi.org/10.1080/09537104.2017.1336210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589745/
https://www.ncbi.nlm.nih.gov/pubmed/28727496
http://dx.doi.org/10.1080/09537104.2017.1336210

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