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Modulation of VEGF-induced migration and network formation by lymphatic endothelial cells: Roles of platelets and podoplanin

Lymphatic endothelial cells (LEC) express the transmembrane receptor podoplanin whose only known endogenous ligand CLEC-2 is found on platelets. Both podoplanin and CLEC-2 are required for normal lymphangiogenesis as mice lacking either protein develop a blood-lymphatic mixing phenotype. We investig...

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Detalles Bibliográficos
Autores principales:	Langan, Stacey A., Navarro-Núñez, Leyre, Watson, Steve P., Nash, Gerard B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589745/ https://www.ncbi.nlm.nih.gov/pubmed/28727496 http://dx.doi.org/10.1080/09537104.2017.1336210

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