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METTL3 facilitates tumor progression via an m(6)A-IGF2BP2-dependent mechanism in colorectal carcinoma

BACKGROUND: Colorectal carcinoma (CRC) is one of the most common malignant tumors, and its main cause of death is tumor metastasis. RNA N(6)-methyladenosine (m(6)A) is an emerging regulatory mechanism for gene expression and methyltransferase-like 3 (METTL3) participates in tumor progression in seve...

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Detalles Bibliográficos
Autores principales: Li, Ting, Hu, Pei-Shan, Zuo, Zhixiang, Lin, Jin-Fei, Li, Xingyang, Wu, Qi-Nian, Chen, Zhan-Hong, Zeng, Zhao-Lei, Wang, Feng, Zheng, Jian, Chen, Demeng, Li, Bo, Kang, Tie-Bang, Xie, Dan, Lin, Dongxin, Ju, Huai-Qiang, Xu, Rui-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589893/
https://www.ncbi.nlm.nih.gov/pubmed/31230592
http://dx.doi.org/10.1186/s12943-019-1038-7