Cargando…

METTL3 facilitates tumor progression via an m(6)A-IGF2BP2-dependent mechanism in colorectal carcinoma

BACKGROUND: Colorectal carcinoma (CRC) is one of the most common malignant tumors, and its main cause of death is tumor metastasis. RNA N(6)-methyladenosine (m(6)A) is an emerging regulatory mechanism for gene expression and methyltransferase-like 3 (METTL3) participates in tumor progression in seve...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Ting, Hu, Pei-Shan, Zuo, Zhixiang, Lin, Jin-Fei, Li, Xingyang, Wu, Qi-Nian, Chen, Zhan-Hong, Zeng, Zhao-Lei, Wang, Feng, Zheng, Jian, Chen, Demeng, Li, Bo, Kang, Tie-Bang, Xie, Dan, Lin, Dongxin, Ju, Huai-Qiang, Xu, Rui-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589893/ https://www.ncbi.nlm.nih.gov/pubmed/31230592 http://dx.doi.org/10.1186/s12943-019-1038-7

Ejemplares similares

METTL14 Facilitates the Metastasis of Pancreatic Carcinoma by Stabilizing LINC00941 in an m6A-IGF2BP2-Dependent Manner
por: Lu, Jiawei, et al.
Publicado: (2023)

Downregulation of METTL14 improves postmenopausal osteoporosis via IGF2BP1 dependent posttranscriptional silencing of SMAD1
por: Huang, Chaoqing, et al.
Publicado: (2022)

LncRNA LINRIS stabilizes IGF2BP2 and promotes the aerobic glycolysis in colorectal cancer
por: Wang, Yun, et al.
Publicado: (2019)

METTL3-IGF2BP3-axis mediates the proliferation and migration of pancreatic cancer by regulating spermine synthase m6A modification
por: Guo, Zhenyun, et al.
Publicado: (2022)

Targeting IGF2BP3 in Cancer
por: Liu, Xin, et al.
Publicado: (2023)

METTL3/IGF2BP2 axis affects the progression of colorectal cancer by regulating m6A modification of STAG3
por: Yi, Jianmei, et al.
Publicado: (2023)

METTL3/IGF2BP3 axis inhibits tumor immune surveillance by upregulating N(6)-methyladenosine modification of PD-L1 mRNA in breast cancer
por: Wan, Weijun, et al.
Publicado: (2022)

Genetic and pharmacological inhibition of METTL3 alleviates renal fibrosis by reducing EVL m6A modification through an IGF2BP2‐dependent mechanism
por: Ni, Wei‐Jian, et al.
Publicado: (2023)

METTL3-Modulated circUHRF2 Promotes Colorectal Cancer Stemness and Metastasis through Increasing DDX27 mRNA Stability by Recruiting IGF2BP1
por: Chen, Miao, et al.
Publicado: (2023)

N6-Methyladenosine Methyltransferase METTL3 Promotes Angiogenesis and Atherosclerosis by Upregulating the JAK2/STAT3 Pathway via m6A Reader IGF2BP1
por: Dong, Guo, et al.
Publicado: (2021)

Role of IGF2BP3 in trophoblast cell invasion and migration
por: Li, W, et al.
Publicado: (2014)

IGF2BP2 maybe a novel prognostic biomarker in oral squamous cell carcinoma
por: Wang, Xiangpu, et al.
Publicado: (2022)

N(6)-methyladenosine (m(6)A) methyltransferase METTL3 regulates sepsis-induced myocardial injury through IGF2BP1/HDAC4 dependent manner
por: Shen, Hao, et al.
Publicado: (2022)

IGF2BP2 Polymorphisms Are Associated with Clinical Characteristics and Development of Oral Cancer
por: Chou, Chia-Hsuan, et al.
Publicado: (2020)

PRMT3-mediated arginine methylation of IGF2BP1 promotes oxaliplatin resistance in liver cancer
por: Shi, Yunxing, et al.
Publicado: (2023)

Circular RNA circIGF2BP3 Promotes the Proliferation and Differentiation of Chicken Primary Myoblasts
por: Wang, Xiaotong, et al.
Publicado: (2023)

METTL14 inhibits malignant progression of oral squamous cell carcinoma by targeting the autophagy-related gene RB1CC1 in an m6A-IGF2BP2-dependent manner
por: Liang, Jianfeng, et al.
Publicado: (2023)

Expression of the cancer testis antigen IGF2BP3 in colorectal cancers; IGF2BP3 holds promise as a specific immunotherapy target
por: Shantha Kumara, HMC, et al.
Publicado: (2015)

IGF2BP3 facilitates cell proliferation and tumorigenesis via modulation of JAK/STAT signalling pathway in human bladder cancer
por: Huang, Wei, et al.
Publicado: (2020)

Investigation of Igf-1, Igf-Bp3 and Igf-Bp5 levels in umbilical cord blood of infants with developmental dysplasia of the hip
por: DEMİREL, Esra, et al.
Publicado: (2023)

RNA N6-methyladenosine reader IGF2BP3 interacts with MYCN and facilitates neuroblastoma cell proliferation
por: Zhu, Kai, et al.
Publicado: (2023)

RBM15 facilitates laryngeal squamous cell carcinoma progression by regulating TMBIM6 stability through IGF2BP3 dependent
por: Wang, Xin, et al.
Publicado: (2021)

Circular RNA circEYA3 promotes the radiation resistance of hepatocellular carcinoma via the IGF2BP2/DTX3L axis
por: Hu, Pan, et al.
Publicado: (2023)

IGF2BP3 as a Prognostic Biomarker in Well-Differentiated/Dedifferentiated Liposarcoma
por: Klingbeil, Kyle D., et al.
Publicado: (2023)

Investigation of IGF1, IGF2BP2, and IGFBP3 variants with lymph node status and esophagogastric junction adenocarcinoma risk
por: Tang, Weifeng, et al.
Publicado: (2018)

METTL3‐mediated N6‐methyladenosine exacerbates ferroptosis via m6A‐IGF2BP2‐dependent mitochondrial metabolic reprogramming in sepsis‐induced acute lung injury
por: Zhang, Hao, et al.
Publicado: (2023)

LCAT1 is an oncogenic LncRNA by stabilizing the IGF2BP2-CDC6 axis
por: Yang, Juze, et al.
Publicado: (2022)

Identification of the function and mechanism of m6A reader IGF2BP2 in Alzheimer’s disease
por: Deng, Yanyao, et al.
Publicado: (2021)

Parkin regulates IGF2BP3 through ubiquitination in the tumourigenesis of cervical cancer
por: Sun, Xin, et al.
Publicado: (2023)

Identification of IGF2BP3 as an Adverse Prognostic Biomarker of Gliomas
por: Sun, Chao, et al.
Publicado: (2021)

Igf2bp3 maintains maternal RNA stability and ensures early embryo development in zebrafish
por: Ren, Fan, et al.
Publicado: (2020)

Inhibition of the m(6)A reader IGF2BP2 as a strategy against T-cell acute lymphoblastic leukemia
por: Feng, Panpan, et al.
Publicado: (2022)

microRNA-670 modulates Igf2bp1 expression to regulate RNA methylation in parthenogenetic mouse embryonic development
por: Hao, Jindong, et al.
Publicado: (2020)

IGF2BP3-induced activation of EIF5B contributes to progression of hepatocellular carcinoma cells
por: LI, XIAOYIN, et al.
Publicado: (2023)

IGF2BP2 acts as a m(6)A modification regulator in laryngeal squamous cell carcinoma through facilitating CDK6 mRNA stabilization
por: Tang, Xiaojun, et al.
Publicado: (2023)

SP1-induced lncRNA MCF2L-AS1 promotes cisplatin resistance in ovarian cancer by regulating IGF2BP1/IGF2/MEK/ERK axis
por: Zhu, Yan, et al.
Publicado: (2022)

Overexpression of IGF2BP3 as a Potential Oncogene in Ovarian Clear Cell Carcinoma
por: Liu, Huidi, et al.
Publicado: (2020)

IGF2BP2-meidated m(6)A modification of CSF2 reprograms MSC to promote gastric cancer progression
por: Ji, Runbi, et al.
Publicado: (2023)

CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis
por: Zhang, Wei, et al.
Publicado: (2021)

Enhancement of LIN28B-induced hematopoietic reprogramming by IGF2BP3
por: Wang, Saifeng, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_2hf3vv26466ilp84k4q01fd55h