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Cell cycle–dependent association of polo kinase Cdc5 with CENP-A contributes to faithful chromosome segregation in budding yeast

Evolutionarily conserved polo-like kinase, Cdc5 (Plk1 in humans), associates with kinetochores during mitosis; however, the role of cell cycle–dependent centromeric (CEN) association of Cdc5 and its substrates that exclusively localize to the kinetochore have not been characterized. Here we report t...

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Detalles Bibliográficos
Autores principales: Mishra, Prashant K., Olafsson, Gudjon, Boeckmann, Lars, Westlake, Timothy J., Jowhar, Ziad M., Dittman, Lauren E., Baker, Richard E., D’Amours, Damien, Thorpe, Peter H., Basrai, Munira A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589903/
https://www.ncbi.nlm.nih.gov/pubmed/30726152
http://dx.doi.org/10.1091/mbc.E18-09-0584