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MAPK modulation of yeast pheromone signaling output and the role of phosphorylation sites in the scaffold protein Ste5

Mitogen-activated protein kinases (MAPKs) mediate numerous eukaryotic signaling responses. They also can modulate their own signaling output via positive or negative feedback loops. In the yeast pheromone response pathway, the MAPK Fus3 triggers negative feedback that dampens its own activity. One t...

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Detalles Bibliográficos
Autores principales: Winters, Matthew J., Pryciak, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589907/
https://www.ncbi.nlm.nih.gov/pubmed/30726174
http://dx.doi.org/10.1091/mbc.E18-12-0793