Gestational Arsenic Trioxide Exposure Acts as a Developing Neuroendocrine-Disruptor by Downregulating Nrf2/PPARγ and Upregulating Caspase-3/NF-ĸB/Cox2/BAX/iNOS/ROS

The goal of this investigation was to evaluate the effects of gestational administrations of arsenic trioxide (ATO; As(2)O(3)) on fetal neuroendocrine development (the thyroid-cerebrum axis). Pregnant Wistar rats were orally administered ATO (5 or 10 mg/kg) from gestation day (GD) 1 to 20. Both dose...

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Detalles Bibliográficos
Autores principales: Ahmed, R. G., El-Gareib, A. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589982/
https://www.ncbi.nlm.nih.gov/pubmed/31258454
http://dx.doi.org/10.1177/1559325819858266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589982/
https://www.ncbi.nlm.nih.gov/pubmed/31258454
http://dx.doi.org/10.1177/1559325819858266

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