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Pediatric Anthracycline‐Induced Cardiotoxicity: Mechanisms, Pharmacogenomics, and Pluripotent Stem‐Cell Modeling

Anthracycline‐induced cardiotoxicity (ACT) is a severe adverse drug reaction for a subset of children treated with anthracyclines as part of chemotherapy protocols. The identification of genetic markers associated with increased ACT susceptibility has clinical significance toward improving patient c...

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Detalles Bibliográficos
Autores principales: Tripaydonis, Anne, Conyers, Rachel, Elliott, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590110/
https://www.ncbi.nlm.nih.gov/pubmed/30460992
http://dx.doi.org/10.1002/cpt.1311